Journal Club 220513

Nifuji introduced a paper entitled “Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators , Nature 2018 Jan 11;553(7687):228-232” , which described genes involved in the control of L1 retrotransposition in human cells. It also described that HUSH proteins and MORC2 can selectively bind evolutionarily young, full-length L1s located within transcriptionally permissive euchromatic environments, and promote deposition of histone H3 Lys9 trimethylation (H3K9me3) for transcriptional silencing.

コメントを残す

メールアドレスが公開されることはありません。 が付いている欄は必須項目です

Journal club

前の記事

Journal Club 220427
Journal club

次の記事

Journal club 220603