Nifuji introduced 2 papers “Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM ( JBMR. 2020 35(11):2252-2264. doi: 10.1002/jbmr.4120. and ) and RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis (JCI Insight. 2017;2(7):e90517.)” which showed new mechanisms regulating root formation and osteoclast differentiation, respectively.